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Publications

Selected Peer-Reviewed Articles:

  1. Elliott JT, Henderson E, Streeter SS, Demidov V, Han X, Tang Y, Sottosanti JS, Bateman L, Brůža P, Jiang S, Gitajn IL. Fluorescence-guided and molecularly-guided debridement: identifying devitalized and infected tissue in orthopaedic trauma. Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12361:1236108. doi: 10.1117/12.2661243. Epub 2023 Mar 14. PMID: 37056956; PMCID: PMC10091097.
  2. Tang Y, Gitajn IL, Cao X, Han X, Elliott JT, Yu X, Bateman LM, Malskis BS, Fisher LA, Sin JM, Henderson ER, Pogue BW, Jiang S. Automated motion artifact correction for dynamic contrast-enhanced fluorescence imaging during open orthopedic surgery. Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12361:1236104. doi: 10.1117/12.2650028. Epub 2023 Mar 14. PMID: 37034556; PMCID: PMC10078951.
  3. Streeter SS, Ray GS, Bateman LM, Hebert KA, Bushee FE, Rodi SW, Gitajn IL, Ahn J, Singhal S, Martin ND, Bernthal NM, Lee C, Obremskey WT, Schoenecker JG, Elliott JT, Henderson ER. Early identification of life-threatening soft-tissue infection using dynamic fluorescence imaging: first-in-kind clinical study of first-pass kinetics. Proc SPIE Int Soc Opt Eng. 2023 Jan-Feb;12361:123610B. doi: 10.1117/12.2648408. Epub 2023 Mar 14. PMID: 37034555; PMCID: PMC10078977.
  4. Marois M, Olson JD, Wirth DJ, Elliott JT, Fan X, Davis SC, Paulsen KD, Roberts DW. A birefringent spectral demultiplexer enables fast hyper-spectral imaging of protoporphyrin IX during neurosurgery. Commun Biol. 2023 Mar 30;6(1):341. doi: 10.1038/s42003-023-04701-9. PMID: 36991092; PMCID: PMC10060426.
  5. Elliott JT, Jiang S, Henderson ER, Slobogean GP, O'Hara NN, Xu C, Xin J, Han X, Christian ML, Gitajn IL. Intraoperative assessment of bone viability through improved analysis and visualization of dynamic contrast-enhanced fluorescence imaging: technique report. OTA Int. 2022 Nov 30;5(4):e222. doi: 10.1097/OI9.0000000000000222. PMID: 36569105; PMCID: PMC9782343.
  6. Streeter SS, Hebert KA, Bateman LM, Ray GS, Dean RE, Geffken KT, Resnick CT, Austin DC, Bell JE, Sparks MB, Gibbs SL, Samkoe KS, Gitajn IL, Elliott JT, Henderson ER. Current and Future Applications of Fluorescence Guidance in Orthopaedic Surgery. Mol Imaging Biol. 2023 Feb;25(1):46-57. doi: 10.1007/s11307-022-01789-z. Epub 2022 Nov 29. PMID: 36447084; PMCID: PMC10106269.
  7. Demidov VV, Clark MA, Streeter SS, Sottosanti JS, Gitajn IL, Elliott JT. High-energy open-fracture model with initial experience of fluorescence-guided bone perfusion assessment. J Orthop Res. 2023 May;41(5):1040-1048. doi: 10.1002/jor.25443. Epub 2022 Oct 3. PMID: 36192829; PMCID: PMC10067537.
  8. Tang Y, Sin JM, Gitajn IL, Cao X, Han X, Elliott JT, Yu X, Christian ML, Bateman L, Chockbengboun T, Henderson ER, Pogue BW, Jiang S. Dynamic contrast- enhanced fluorescence imaging compared with MR imaging in evaluating bone perfusion during open orthopedic surgery. Proc SPIE Int Soc Opt Eng. 2022 Jan- Feb;11943:119430C. doi: 10.1117/12.2608382. Epub 2022 Mar 4. PMID: 36061412; PMCID: PMC9430826.
  9. Han X, Demidov V, Vaze VS, Jiang S, Gitajn IL, Elliott JT. Spatial and temporal patterns in dynamic-contrast enhanced intraoperative fluorescence imaging enable classification of bone perfusion in patients undergoing leg amputation. Biomed Opt Express. 2022 May 3;13(6):3171-3186. doi: 10.1364/BOE.459497. PMID: 35781962; PMCID: PMC9208615.
  10. Murphy EK, Klein SB, Hamlin A, Anderson JE, Minichiello JM, Lindqwister AL, Moodie KL, Wanken ZJ, Read JT, Borza VA, Elliott JT, Halter RJ, Vaze VS, Paradis NA. Detection of subclinical hemorrhage using electrical impedance: a porcine study. Physiol Meas. 2022 May 25;43(5). doi: 10.1088/1361-6579/ac6cc6. PMID: 35508144.
  11. Sepehri A, Slobogean GP, O'Hara NN, McKegg P, Rudnicki J, Atchison J, O'Toole RV, Sciadini MF, LeBrun CT, Nascone JW, Johnson AJ, Gitajn IL, Elliott JT, Scolaro JA, Pensy RA. Assessing Soft Tissue Perfusion Using Laser-Assisted Angiography in Tibial Plateau and Pilon Fractures: A Pilot Study. J Orthop Trauma. 2021 Dec 1;35(12):626-631. doi: 10.1097/BOT.0000000000002100. PMID: 34797781; PMCID: PMC8918020.
  12. Jiang S, Elliott JT, Xing J, Cao X, Yu X, Han X, Dabrowski RE, Christian ML, Henderson ER, Pogue BW, Gitajn IL. ICG-based dynamic contrast- enhanced fluorescence imaging guided open orthopaedic surgery: pilot patient study. Proc SPIE Int Soc Opt Eng. 2021 Mar;11625:116250W. Epub 2021 Mar 5. PMID: 36082047; PMCID: PMC9451047.
  13. JT Elliott, RR Addante, GP Slobogean, S Jiang, ER Henderson, BW Pogue, IL Gitajn. Intraoperative fluorescence perfusion assessment should be corrected by a measured subject-specific arterial input function. J Biomed Opt 2020. https://doi.org/10.1117/1.JBO.25.6.066002
  14. JT Elliott, DJ Wirth, SC Davis, JD Olson, NE Simmons, TC Ryken, KD Paulsen, DW Roberts. Seeing the light: Improving the usability of fluorescence-guided surgery by adding an optimized secondary light source. medRxiv 2020. https://doi.org/10.1101/2020.03.09.20032359
  15. JT Elliott, S Jiang, BW Pogue, IL Gitajn. Bone-specific kinetic model to quantify periosteal and endosteal blood flow using indocyanine green in fluorescence guided orthopedic surgery. J Biophotonics 2019.
  16. JT Elliott, K Marra, LT Evans, et al. Simultaneous in vivo fluorescent markers for perfusion, protoporphyrin metabolism and EGFR expression for optically guided identification of orthotopic glioma. Clin Canc Res 2017. (Featured on the Cover of the May 2017 issue).
  17. JT Elliott, AV Dsouza, K Marra, et al. Microdose fluorescence imaging of ABY-029 on an operating microscope adapted by custom illumination and imaging modules. Biomed Opt Expr 2016.
  18. JT Elliott, AV Dsouza, SC Davis, et al. Review of fluorescence guided surgery visualization and overlay techniques. Biomed Opt Expr 2015; 6(10):3765-3782.
  19. JT Elliott, KS Samkoe, SC Davis, et al. Image-derived arterial input function for quantitative fluorescence imaging of receptor-drug binding in vivo. J Biophotonics 2015; (DOI: 10.1002/jbio.201500162).
  20. JT Elliott, M Diop, LB Morrison, et al. Quantifying cerebral blood flow in an adult pig ischemia model by a depth-resolved dynamic contrast-enhanced optical method. Neuroimage 2014; 94:303-11 1016/j.neuroimage.2014.03.023.

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